567.896 753.6 573 748.496 573 742.2 c 273 264.72 l f* 0 G 438.48 601.68 l f* S 0.075 0.271 0.8 rg 0 G 228.96 446.64 7.2 -4.32 re 164.88 211.56 m 412.68 293.16 l 461.28 312.48 m Q 179.76 476.76 l ET 18 0 0 18 440.16 666.36 Tm f* q 443.52 233.4 l S 329.28 635.76 l 208.8 509.16 l ET f* 253.68 132.36 l 253.8 262.2 l 201.72 493.2 m 0 g 253.32 132.72 l 262.56 633.36 m 192.96 273.48 l 278.88 638.16 l 14.4 253.44 582.48 -15.96 re 452.28 273.96 l 143.4 467.16 l 380.28 549.84 l S 253.8 565.8 l 0.035 0.129 0.384 rg 258.48 242.64 l f* 177.48 149.88 l 269.88 252.96 l 306.96 303.24 0.84 -0.06 re 284.04 542.64 l 0 -1.077 TD Three of the 16 chapters have new authors and have been totally rewritten. 282.96 304.08 7.2 -4.44 re 208.32 261.48 l f* 194.52 566.16 m 218.16 273.48 l 110.64 264.046 118.381 271.68 127.92 271.68 c 450.6 216.6 l f* 458.28 551.88 l 506.28 561.84 0.84 -0.06 re 322.44 313.44 l 498.96 312.6 0.84 -0.06 re 0.005 Tc 280.2 615.96 l 1 0.953 0.882 rg 1 i 1 J 1 j 0.96 w 10 M []0 d S 203.64 588.36 l 306.36 572.64 0.36 -0.06 re 190.2 553.32 m 310.56 520.08 l f* S 210.6 302.76 0.6 -0.06 re 240.6 185.76 6 -4.8 re f* 0000001654 00000 n 451.44 551.52 0.48 -0.06 re 203.28 133.44 l 423.72 596.76 l 143.04 579.03 137.556 573.6 130.8 573.6 c 266.16 514.08 l 398.04 441 l 392.88 180.24 m 338.76 619.2 l 208.92 238.92 l 443.64 600.96 l 567.896 753.6 573 748.496 573 742.2 c 489.12 286.2 l f* 127.56 303.72 l 268.81 591.84 270.96 589.743 270.96 587.16 c 469.08 415.44 0.6 -0.06 re 253.32 219.84 m ( )Tj S 363.96 419.16 l S 215.88 493.32 l 254.64 216.6 l 161.64 259.32 1.56 -0.06 re 329.64 545.64 l 253.56 441.6 0.72 -0.06 re 418.8 167.88 l 158.76 297.24 m 387 308.16 l 293.64 539.52 7.32 -3.72 re S 444.72 408 l 387.72 267 l 380.28 363.48 l 258.72 152.4 l 0.071 0.259 0.769 rg S 375 414.12 0.36 -0.06 re 423.48 169.56 l 304.92 151.08 l 0 g 433.68 414.12 l 233.64 204.84 l f* 360.24 251.16 l 430.8 530.76 l 225.36 386.4 l f* 194.64 639.84 l 305.04 189.96 l 423.96 566.16 l 177.48 250.2 m 277.68 520.68 l f* 240.6 243.36 m 405.72 228.24 l 422.76 174 l 35.64 757.08 540 -720 re 318.24 211.68 m 1 i 1 J 1 j 0.96 w 10 M []0 d 222.96 409.92 l f* 391.92 547.56 l 330.12 204.48 l 360.48 604.92 l 317.16 598.44 l 444.12 146.4 l 220.56 270.96 l 297.12 622.08 l q 310.44 565.92 l 185.76 399.36 l 240.6 245.52 m 253.32 261.72 l s 1 i 1 J 1 j 0.96 w 10 M []0 d 439.8 415.44 0.6 -0.06 re 345.36 543.84 l S 146.28 270.48 l 459.12 567.72 l 326.04 435.12 l 309.12 526.8 l S 333.24 571.68 l f* 266.28 262.08 l 191.28 554.16 l 0 g 177.72 288.84 l S f* 202.8 247.2 m f* f* 1 g 9.96 0 0 9.96 342 197.04 Tm 214.56 441.84 l 278.52 171.6 l f* 455.76 454.44 l S 298.059 294.72 290.64 302.031 290.64 311.04 c 183.48 530.28 l 478.08 299.4 l 149.16 302.04 0.48 -0.06 re f* 293.64 564.72 m 212.4 413.28 0.48 -0.06 re f* f* f* 407.16 530.28 l 297.12 217.8 l S 181.92 189.96 l 293.64 521.76 m 152.16 120.24 m 358.56 435.24 7.08 -4.56 re 294.6 619.92 l 291.12 581.4 l S 39.12 742.2 l 443.4 467.88 l f* 359.52 603.96 l S 219.36 231.12 m 498.24 580.33 493.617 575.76 487.92 575.76 c 166.92 444.48 l 452.88 233.28 l f* 348.36 345.36 l 206.04 573.36 l q 215.4 238.92 l f* 196.2 267.72 l 357.36 268.44 m 411.12 551.16 l 0001326591 00000 n 341.28 526.92 l 206.16 409.56 l S 445.08 402.96 7.2 -7.44 re 427.8 264.72 l W n 232.08 145.8 l BT 0 g 380.28 606.24 m 268.56 545.76 l (\(1900s\))Tj 329.76 615.84 l S 228.96 427.92 7.2 -2.28 re f* 164.64 392.4 l 212.4 415.56 0.48 -0.06 re 177.48 653.76 l 225.36 297.24 l 0 -1.085 TD 246.48 189.6 l 268.56 444.84 l S S 306.36 571.92 0.36 -0.06 re 278.52 210.12 l S f* 355.08 214.2 l f* Q 170.88 125.52 l f* 257.76 189.96 l D2_W-AAOYrQB#1?A"!b:SE(F918eeh8jAY<=rrZNh2@7+-WHA:Z! 221.4 625.32 l 432 613.68 l 407.16 175.2 l 139.68 280.08 m 257.88 222.72 l 256.44 344.76 l 340.8 303.48 0.6 -0.06 re f* 243 624 l 0 G 215.4 541.44 l (tRNA)Tj 183 144.24 l 547.2 195.36 l 263.28 367.08 m 333.36 574.08 0.36 -0.06 re 170.88 514.56 l 371.88 564.96 l S 519.72 140.52 l 470.04 414.24 0.36 -0.06 re 331.56 415.68 m 462.36 231.48 l 190.2 557.88 m 145.68 283.2 l 44.224 39.72 39.12 44.824 39.12 51.12 c T* 0001338267 00000 n 152.4 636.48 l f* 210 234.48 l 299.04 492.36 l 246.48 639.48 l 355.08 542.88 l f* S 0.039 0.145 0.431 rg 279 204.72 l 259.32 219.84 l f* 182.52 624.36 l 278.88 302.88 0.6 -0.06 re f* 183 625.32 l 456.6 256.56 l 429.6 443.64 m 1 g 291.12 217.8 6 -3.48 re 393.24 189.96 l 438.12 519 l 215.4 143.76 l 230.64 477.24 l 423.72 600 l 182.52 624.36 l 311.4 311.4 l 398.88 594.24 l 152.64 133.44 l 155.16 259.2 m 196.68 395.28 l S BT 203.28 261.48 l 284.64 562.8 l 189.36 226.32 1.56 -0.06 re S 221.4 493.56 l 147.96 293.28 l 169.2 257.52 l 113.4 301.8 0.48 -0.06 re 513.12 325.08 l 314.04 564.96 l 419.76 408.36 l 205.8 511.2 l 470.4 438.84 l 104.4 248.16 l f* 508.92 426.12 0.96 -0.06 re 261.96 546.84 l 351.36 407.4 l 326.04 437.52 m 154.8 573.6 l 183.12 204.84 l 178.92 580.56 l 229.56 622.8 m 159.815 591.84 152.88 598.721 152.88 607.2 c 297.24 243.84 m f* 138.96 547.68 l 221.64 232.68 l 228 225.36 l 1 i 1 J 1 j 2.04 w 10 M []0 d 171.24 494.88 l 460.56 547.8 l 342.96 528.96 l 310.56 147.72 l f* 170.4 125.52 l f* 0 G 319.08 574.08 0.36 -0.06 re 399.12 535.08 l 356.52 164.76 l 284.28 638.16 l 365.64 555.84 l 246.12 526.68 l f* f* 477.48 361.08 l 296.52 266.64 l 411.12 597.48 l 300.96 545.76 l 0.084 Tw 218.28 298.68 l 305.04 527.4 l 365.64 504 l f* 14.4 207.36 582.48 -5.4 re 470.52 296.64 l 342.72 529.08 l 218.16 385.08 l 455.76 437.64 m f* 207.48 454.68 l 0 g 381.36 232.92 l 401.04 420.24 m f* S 228 147.84 l 438.12 137.16 m 373.68 604.56 l 320.76 277.68 l 355.44 566.16 l 153.36 394.08 m 398.16 440.64 l Q f* 326.04 507.24 l 266.16 635.16 l 217.68 249.48 l f* 268.56 416.4 l f* 443.28 583.44 l 338.64 233.16 l 287.88 644.88 l 202.8 247.2 l q 308.28 303.6 l 246.6 218.88 l 14.4 275.76 582.48 -10.08 re 266.4 204.84 l 270.96 573.72 0.36 -0.06 re 377.04 282.282 385.212 290.4 395.28 290.4 c 259.32 255.96 l 152.16 637.44 l 386.52 248.52 l f* W n f* 0 g 201.72 493.2 m 317.88 622.32 l 495.48 421.68 0.96 -0.06 re 416.28 267.12 l 293.16 572.04 0.36 -0.06 re 379.44 273.12 l 355.08 599.76 m 234.24 547.92 l 488.16 534.6 m -0.103 Tw 335.52 243.36 l 275.4 167.28 l 202.2 177.36 l 261.24 441.24 m 388.2 499.44 l 196.32 655.44 m f* 368.64 540.84 l 301.064 298.56 294.72 304.85 294.72 312.6 c 371.04 572.88 0.36 -0.06 re 152.64 580.8 m 0 G (U)Tj 396.96 219.96 l 182.52 533.52 l W n 454.56 429.24 l 278.52 140.4 m 272.16 615.24 l 439.56 204.24 m f* 271.8 151.2 l 2.41 0 TD 0.002 Tc 164.16 502.32 l f* 208.8 562.32 l 320.16 616.44 m f* 342.72 367.8 m f* S 1 i 1 J 1 j 0.24 w 10 M []0 d f* -208.2 356.4 m 461.409 445.44 462 444.795 462 444 c S S f* 411 550.8 l 306.06 226.32 m f* 196.56 547.8 m 177.48 179.28 m 216.96 251.28 l 221.4 117.72 l 423.48 445.56 l 9.96 0 0 9.96 338.4 373.08 Tm 373.68 562.8 l S 221.28 653.4 l S 240.72 525.96 l 259.2 638.28 l f* 296.64 244.92 l f* 398.16 268.08 l 204.24 580.68 m 174.6 532.08 l 0 g 201.72 493.2 m 121.572 570 114.96 576.559 114.96 584.64 c f* S 387.24 431.4 l 363.96 419.16 l f* 278.52 624.84 l 218.16 311.88 l 221.76 433.92 l 315.468 622.56 322.08 616.001 322.08 607.92 c 246.6 617.28 l 310.32 519.36 l 187.2 231.24 8.52 -0.06 re S f* 153.36 407.28 m 323.16 184.44 l 333.24 443.28 l 1 i 1 J 1 j 0.96 w 10 M []0 d 259.8 225.72 l 361.08 604.32 l -0.436 -1.203 TD 251.28 224.76 l 432.96 566.613 436.401 570 440.64 570 c 195.6 235.2 1.68 -0.06 re 434.4 420.6 l 317.16 144.72 l 326.04 437.52 l 0.13 Tw 228 205.2 l f* 0 g 419.04 234.24 l 405.48 600 l 412.8 493.08 l 241.44 149.64 l 385.92 429.84 l f* 380.28 307.68 l 254.28 150.36 l 177.48 616.32 l 369.36 309.72 l 216.96 580.56 l 181.92 580.68 l 284.16 189.72 l 361.15 288.96 367.44 282.67 367.44 274.92 c Q 430.56 446.64 l 495.12 287.4 0.72 -0.06 re 306.36 573.48 0.36 -0.06 re 285.36 230.76 8.16 -0.06 re 371.16 572.04 0.6 -0.06 re 293.16 573.72 0.36 -0.06 re f* 345.36 224.88 m 288 439.44 0.36 -0.06 re f* 1 i 1 J 1 j 0.96 w 10 M []0 d 335.28 580.56 l 291.6 204.72 m 15.96 0 0 15.96 106.44 190.32 Tm f* f* 1 g 527.76 248.64 l 411.6 228 l 132.24 435.12 l 0 g 438.12 562.8 m 300 546.36 l 197.16 444.96 l 423.72 595.08 l 369.12 580.68 m 322.68 153.12 l 370.68 227.88 m 152.64 133.2 l 502.8 272.28 m 14.4 513.36 582.48 -5.4 re 540 287.788 528.932 276.72 515.28 276.72 c 259.32 246.6 l 196.56 588.36 l 197.16 437.16 l 196.56 593.52 l 360.48 606 l 335.52 248.4 l 1 g 202.8 639.6 l /F4 1 Tf f* 498.24 286.2 0.96 -0.06 re f* 332.64 546.24 l 14.4 207.36 582.48 -5.4 re 128.16 344.88 l 405.48 549.36 l 293.64 508.8 m 0 G 185.76 418.44 l 478.44 299.16 l 1 g 506.28 450.48 0.84 -0.06 re S 425.64 399.36 l 243 302.4 0.48 -0.06 re 207.24 635.64 l (R = rudimentary wing)Tj 230.64 477.24 l 219.96 204.48 l f* S f* S 181.92 204.6 m f* 253.32 526.44 m 394.44 574.8 0.6 -0.06 re 370.68 166.68 m 317.16 180.72 l 212.04 429.6 l 438.48 240.96 l 240.72 131.16 l 155.76 229.92 l 495.48 424.92 0.96 -0.06 re 367.44 248.053 360.828 241.44 352.68 241.44 c S 257.76 204.6 l 167.64 437.64 l 337.2 612.6 l W n 272.04 508.56 l 445.8 409.32 l f* 257.76 285.24 l Q 445.08 408.6 l S 342 302.88 0.48 -0.06 re 195.36 495.36 l 291.12 552.84 l 231.96 547.92 l 393.96 444.24 l f* 355.08 217.8 l 280.68 574.32 0.6 -0.06 re 423.48 545.4 7.32 -4.56 re 0 g Q 0001332726 00000 n 194.64 581.416 200.93 587.76 208.68 587.76 c 498 231.48 l 429.96 531 l 228.96 492.48 l 164.88 594 6 -3 re (necessary to produce a finished RNA, and post-translational processing of)Tj S S 218.04 261.84 l 376.2 233.88 l 342.72 367.8 l 1 g S S 0001323040 00000 n 461.16 391.2 l S 165.36 501.96 l f* 202.8 442.44 l W n 305.04 619.68 l (P)Tj 202.8 651.24 l 95.16 198.6 l 245.16 580.68 l 495.24 545.76 l 589.8 233.88 l 178.92 204.6 l 271.8 527.4 l 411.6 542.88 l 219.96 471.48 l 469.56 561.36 l f* 185.76 266.4 l 344.28 573.84 0.36 -0.06 re f* 1 g /F6 1 Tf f* 0.569 G q S f* 268.44 449.28 l 293.64 435.24 m f* 158.16 169.08 l 170.88 214.8 l 116.16 264.67 122.45 270.96 130.2 270.96 c 228.24 624 l 477.72 274.2 l 164.88 516.6 l 245.64 527.28 l S 206.04 557.76 l 278.796 354 276 356.581 276 359.76 c f* 417.24 234.12 l 424.08 219.48 l 233.52 246.72 l 404.64 587.16 m f* 398.88 176.16 l 215.4 229.08 6 -7.44 re 131.64 547.2 l 1 g f* 165.36 565.8 l 293.88 436.68 l 166.92 503.64 l 196.2 111 l 438.12 601.8 l 194.52 566.16 l 72.12 168.6 467.88 -95.88 re 304.56 612.72 l 0.051 0.192 0.569 rg S 184.2 589.32 m 14.4 273.48 582.48 -5.4 re )Tj f* 266.16 591 m 125.28 553.56 l 212.64 565.32 l 406.92 414.48 0.48 -0.06 re f* 228 607.44 m 397.8 441.12 l S f* 0.001 Tc 0 g 324.24 572.598 316.122 564.48 306.12 564.48 c f* 0 G 354.96 430.8 l 228.96 545.64 m 466.08 341.28 l 380.76 575.28 l 315.24 427.08 m 508.8 452.52 1.32 -0.06 re 14.4 513.36 582.48 -5.4 re 219.96 204.6 l 398.52 595.08 l 380.28 603.72 6 -2.76 re 380.76 597.96 l 257.76 566.16 l 164.88 174 l 182.88 248.76 l 180.24 302.04 0.36 -0.06 re 266.16 625.08 l 268.56 407.88 l 305.88 204.6 l 163.8 595.08 l 320.76 357.24 l 293.64 570.36 l (demonstrate that complex organic reactions could be accomplished)Tj 225.24 266.88 l 155.16 135.24 l f* S 513.36 259.92 l 319.32 224.52 l 476.76 280.08 m S f* 307.92 300.48 0.36 -0.06 re B* 184.08 451.92 l 1 g 385.2 573.36 0.48 -0.06 re 168 573.12 l S 295.8 573.12 0.48 -0.06 re 259.32 182.76 l 309.72 300.84 0.72 -0.06 re 234.3 215.042 236.27 213.12 238.68 213.12 c 0 g S 358.32 233.52 1.8 -0.06 re 163.44 552.36 l 360.24 542.4 l S 405.331 326.64 412.32 319.759 412.32 311.28 c S 19.479 0 TD 506.76 262.8 l b* 153.96 254.4 l 138.36 435.36 l 128.16 456.48 l 163.68 272.4 l f* 15.96 0 0 15.96 105.36 298.68 Tm f* f* 1 J 1 j 187.56 407.52 l q 228.36 522.24 l 403.2 534.6 l [(al)12(lel)12(e.)]TJ 229.56 566.16 l f* 157.8 635.76 l 170.52 447.12 l 274.32 264.588 274.159 264.48 273.96 264.48 c 152.16 667.44 l 229.56 624.84 l S 147.36 230.88 l 122.64 409.68 l 397.44 566.16 l 135.72 241.44 l 456.6 449.76 l S 390.96 555.6 l 0 G 441.36 504.6 l 246.6 180.96 l 468.36 555.96 l 380.28 594.24 m 0 G q f* 153.6 261.36 l 246.12 130.92 l T* 534 199.44 l 180.72 603.61 176.097 599.04 170.4 599.04 c S 156.12 509.4 l 477.36 287.4 l f* q 219.96 432.96 l 191.16 297.24 l 215.88 627 l 396.12 419.16 l 215.88 519.48 l 225.36 397.32 l S f* 385.92 597.36 l f* 177.48 520.32 m 207.72 259.44 l 438 412.8 l 1 g 444 129 l 380.28 552.6 6 -2.76 re q 234 271.2 l 395.16 545.76 l 495.48 421.56 0.96 -0.06 re W n f* 195.48 234.84 1.68 -0.06 re 107.28 450.72 l q 280.68 614.16 l 0.047 0.169 0.506 rg 202.8 443.76 l 299.04 545.76 m 308.04 249.6 l 410.64 226.8 l 308.04 528.96 l 256.92 573.24 0.48 -0.06 re 394.92 594.24 l 445.08 426.96 m 435.72 412.8 l 318.6 154.08 l f* 269.16 525.72 l 228 522 m 189.12 312.6 m f* 236.16 449.88 l 398.88 230.88 l 215.04 567.84 l 191.16 442.08 1.92 -0.06 re 323.16 144.96 l 196.8 436.44 l 261.36 317.103 263.51 319.2 266.16 319.2 c 324.96 234.6 l 294.12 472.08 l 153.36 359.52 l f* 417 255.96 l 501.12 255.6 m S 335.76 558.36 l 172.44 574.08 l 466.2 571.8 l 393.24 545.76 l 208.32 204.72 l 169.92 503.64 l 317.16 157.32 l 240.6 149.16 l S S (VWX)Tj 335.52 615.12 l 157.2 635.4 l 259.08 255.48 l 315.36 288.72 l 0.059 0.212 0.631 rg 220.92 251.28 l 14.4 535.68 582.48 -5.28 re 352.68 314.88 l 183.48 134.52 l 0001320798 00000 n f* 302.4 590.799 305.841 594.24 310.08 594.24 c 487.8 229.08 l 1 g 228.48 260.52 l f* 198.48 33.6 l 419.28 297.6 l (Fundamentals)Tj W n 272.88 216.6 l 317.16 625.2 l 177.48 241.44 m W n 1 g f* 281.16 154.56 l 394.56 545.76 m f* 0.003 Tc 212.4 301.2 0.48 -0.06 re 467.4 327.12 l 323.64 459.6 m f* /F8 1 Tf 514.8 258.84 l 16.92 0 0 16.92 177.24 495.84 Tm 384.12 250.56 l 215.4 531.72 m 171.24 581.28 l 212.4 301.44 0.36 -0.06 re 201.6 409.08 l S 125.28 230.52 l 255.24 242.16 l 390.96 519.12 m 229.32 411 l 405.12 412.8 l 495.07 326.64 501.36 320.35 501.36 312.6 c 155.28 306.48 l 426.6 547.68 l 148.32 280.2 l q 471.12 302.64 l 0.602 0 TD 253.8 618.24 l 322.56 520.2 l 131.64 608.88 l 355.08 581.16 l 329.76 228.84 6 -5.76 re 373.2 580.56 l 25.746 0 TD 488.28 547.2 l 321.6 580.68 m 364.32 269.823 359.75 265.2 354.12 265.2 c 322.56 373.44 l 220.8 520.92 l 447.96 186.72 l 440.64 151.08 l 283.2 354.84 l 424.68 568.68 l f* 392.88 174.48 l 232.56 189.96 l 367.68 166.68 l 160.56 297.24 l 494.52 243.6 l f* W n 367.68 229.32 l 424.08 437.28 l f* 39.12 742.2 l S f* ET 438.12 601.2 l 261.24 545.76 l 509.04 423.12 0.84 -0.06 re 354.96 431.16 l 461.76 256.08 l 185.76 453.96 m 195.36 132.24 l -0.004 Tw 253.32 132.6 l 497.16 426.24 1.68 -0.06 re f* 0 J 0 j 506.52 251.88 l 14.4 535.68 582.48 -5.28 re 342.96 545.88 l 0.045 Tw Q S 283.68 156.6 l (1561)Tj 380.76 580.56 l 418.56 603 l 140.76 504.6 l 179.04 626.4 l 181.08 522.48 l f* f* f* 0 g 452.16 266.88 l 357 227.88 l S 157.44 510.84 l 196.2 565.44 l 419.64 309.12 l 183.48 164.64 l 228 258.48 l 1 g S f* 278.52 254.28 m 208.32 575.16 l 453.12 447.713 455.217 450.24 457.8 450.24 c 228.96 414.48 l 153.36 344.88 l 158.16 637.44 l 149.76 304.44 m 263.88 250.68 l S f* 127.521 268.56 124.08 271.947 124.08 276.12 c S Q 323.16 545.16 l B* f* Q 380.16 407.76 l f* 160.56 364.32 l 128.16 407.76 l S 164.88 224.88 l 266.16 625.08 l 463.08 460.68 l S 159.96 442.08 0.48 -0.06 re 286.56 624.12 l 387.36 297.24 l S 389.226 297.36 382.56 303.919 382.56 312 c S 291.24 512.28 l 255.72 620.28 l 386.76 408.36 l 1 i 1 J 1 j 0.96 w 10 M []0 d 411.48 174.48 l 421.32 410.64 l 196.2 649.68 l 342.36 237.12 l W n 318.36 264.72 l 196.68 493.68 l 380.28 267.24 l 221.4 240.84 l 308.88 520.92 l 177.48 182.28 6 -3 re 289.56 308.64 l 408.6 175.2 l 268.44 344.88 m 456 436.56 l 288 592.602 296.118 600.72 306.12 600.72 c S 495.48 311.04 1.2 -0.06 re 147.84 302.16 0.6 -0.06 re S 292.92 204.48 l 423.12 265.44 l f 391.44 266.28 l 447.37 319.2 449.52 317.103 449.52 314.52 c /F4 1 Tf 292.92 189.96 l 377.16 351.72 l 166.92 571.8 l 228 531.72 m (hand border, the middle nucleotides are given across the top, and the 3')Tj 194.52 204.6 m 412.8 419.76 7.2 -5.16 re 329.76 236.88 m 152.16 561.12 l f* 1 g 187.68 268.524 182.196 263.04 175.44 263.04 c f* 386.28 204.96 l 127.56 407.28 l 398.52 189.96 l 259.32 261.72 l 329.76 522.84 l 316.56 299.52 l 310.56 622.92 l 385.56 551.52 0.48 -0.06 re 170.64 307.8 l 470.04 414.84 0.36 -0.06 re 297.24 619.92 m 143.64 595.68 l f* 0 g S 293.52 234.84 1.68 -0.06 re f* 421.32 174 l 165 307.8 l f* 230.52 145.8 l 196.08 204.96 l 386.168 255.6 378.48 263.234 378.48 272.64 c 334.8 246.12 l S 0.34 Tw S S 320.04 234.24 l 355.92 226.92 1.44 -0.06 re 216.96 204.6 l 494.76 498.96 l /F12 1 Tf 14.4 535.68 582.48 -9.96 re S 355.08 590.4 m f* 293.64 545.76 l f* 335.04 244.2 m 502.68 250.08 l 1 g 0 g 6.96 0 0 6.96 265.2 635.76 Tm 140.16 233.4 l 228 502.08 m 322.92 222.84 l 245.88 526.68 l 321 573.72 0.48 -0.06 re 411.12 550.92 l 284.52 258.72 l 386.16 580.68 l f* -0.014 Tw 414.96 553.56 0.84 -0.06 re 164.88 652.2 l 271.92 150.72 l 207.608 237.6 199.92 245.234 199.92 254.64 c f* 191.52 204.6 l 470.88 296.64 l 473.64 415.2 0.48 -0.06 re 177.48 288.36 l f* 279 239.76 l S 165.24 501.84 l 329.76 561.12 6 -2.76 re 361.56 623.16 l 405 517.68 m 283.2 572.16 0.36 -0.06 re 163.2 255.48 1.68 -0.06 re 342.24 303.48 0.48 -0.06 re 284.64 548.88 l 430.2 568.44 l 141.36 235.44 l 177.48 279.36 6 -1.8 re 318.6 240.36 m 206.88 572.52 l 304.56 528.96 l 185.76 393.12 l 317.16 277.68 l 183.48 633.6 l 318.96 409.92 l 322.2 154.08 l f* 192.6 439.08 0.6 -0.06 re 424.32 594.72 l 14.04 0 0 14.04 95.52 544.92 Tm 464.4 318.6 l 1 g f* 1 g 232.56 523.92 m 474.492 254.16 466.32 262.278 466.32 272.28 c 381 598.44 l 381.12 592.399 388.055 599.28 396.6 599.28 c 0 Tr f* 153.72 303.48 l 462.36 436.44 l 275.64 413.64 0.48 -0.06 re 245.16 747.84 m 484.56 361.32 l f* 397.56 569.76 l f* 291.12 590.4 l 180.36 304.08 1.92 -0.06 re f* 386.04 172.8 l 421.32 174 l 290.28 226.44 1.56 -0.06 re 183.48 491.4 l 157.8 267.72 1.92 -0.06 re 164.88 183 l 349.08 234.84 1.8 -0.06 re 323.04 565.92 l 158.16 237.24 l 158.16 466.32 l 532.425 480.84 540 473.211 540 463.8 c 156 263.4 1.68 -0.06 re f* 190.2 511.8 m f* 255.12 603.813 258.561 607.2 262.8 607.2 c 461.52 314.4 l S 381.36 306.36 l f* 264.72 622.32 m q 219.96 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